New perspectives on Clostridioides difficile infection: host dynamics and disease risk

Environmental niches and transmission dynamics of Clostridioides difficile: an underestimated One Health Dimension

Botulism outbreaks in livestock and wildlife: Assessing public health risks through a One Health approach

Comparing the severity of Clostridium perfringens-induced gas gangrene in normal vs. diabetic mice

Potency test of the first commercial vaccine for prevention of Clostridioides difficile infection in piglets

Unraveling the complexities of Clostridioides difficile and Clostridium perfringens Infections: toxigenic profiles and microbiome disruption in latin America

Enterococcus faecalis alters phase variation in Clostridioides difficile

A sugar-rich diet promotes Clostridioides difficile carriage without prior antibiotics and significantly exacerbates both acute disease and long-term colonization

Bacteroides spp impact Clostridioides difficile growth and toxin production in dual species biofilms

Genomic and virulence traits associated with preterm infant-derived Clostridium perfringens strains

Controlling phage–Host dynamics: safeguarding beneficial bacteria and targeting pathogens

PSII, S-layer pillars is essential for Clostridioides difficile life

Dissecting the biosynthetic pathway of the flagellin Type A glycan in Clostridioides difficile strain 630Δerm

Extreme structural diversification of the C. difficile S-layer exoskeletons

An unusual mechanism of action of β-lactam antibiotics in Clostridioides difficile

Botulinum neurotoxins: a distinct subclass of SNARE-cleaving endopeptidases

Botulinum neurotoxins exploit host digestive proteases to boost their oral toxicity via activating OrfXs/P47

Structural basis of C. difficile TcdB toxin inhibition by intestinal bile acids informs design of a therapeutic antitoxin

Clostridial hemolysin beta-pore-forming toxins find their receptors

Intestinal low dose of botulinum neurotoxins facilitate infection by Salmonella and Shigella

Type 2 Immunity Protection from C. difficile Infection

Spatial transcriptomic landscape of the colon repairing from Clostridioides difficile infection

An in vivo genetic selection identifies Clostridioides difficile gene products targeted by the host immune response

Potentially therapeutic antibodies are encoded by the C. difficile infection-induced human memory B cell compartment despite the predominance of non-protective antibodies

FMT promotes type 2 mucosal immune responses with colonic epithelium proliferation in recurrent CDI patients

The complex regulatory network controlling Clostridioides difficile infectious cycle in response to oxidative stress

Cracking the mechanism of EndoM: how it degrades small RNA and controls sporulation initiation in Clostridioides difficile

Flagella and toxins reduce Clostridioides difficile fitness in an inflammation-dependent manner

BrnQ branched-chain amino acid transporters affect toxin production of Clostridium perfringens gas gangrene type A strain ATCC3624

A conserved switch controls virulence, sporulation, and motility in C. difficile

Surface-driven physiological adaptations promote Clostridioides difficile colonization

90 years of Stickland reaction: How clostridial amino acid reductases obtain their pyruvoyl cofactor

Gut mucin fucosylation dictates the entry of botulinum toxin complexes

Spores in contrast: stereoflexible and bile-driven germination in Clostridium

Inter-species contact-dependent suppression of Clostridioides difficile sporulation requires Enterococcus pili

A plasmid-encoded protein modulates sporulation in Paraclostridium sordellii

Strand swapping in the LolA-like protein GerS promotes CwlD amidase activity and spore germination in Clostridioides difficile

Human Gut Microbiome Resiliency Vs Oral Antibiotics

The Receptor binding domain 2 (RBD2) of binary toxin (CDT) as a promising vaccine candidate protects both mice and hamsters against CDI challenge

Mucosal vaccination of inactivated Clostridioides difficile toxins and novel surface antigens clears colonization and promotes host survival

An overview of the incidence of C. difficile infection around the world, with a focus on France